Tumour nuclear size heterogeneity as a biomarker for post-radiotherapy outcomes in gynecological malignancies
Despite low accuracy, tumour nuclear size heterogeneity aided prognostication over standard clinical variables and was associated with outcomes following radiotherapy in gynecological SCC. This highlights the potential importance of personalized multiscale dosimetry and warrants further large-scale pan-cancer studies.
Authors
- Boris Bahoric
- Shirin Abbasinejad Enger (ORCID: https://orcid.org/0000-0002-6037-0615)
- Manuela Pelmus (ORCID: https://orcid.org/0000-0002-3725-6259)
- Harry Glickman
- Farhad Maleki (ORCID: https://orcid.org/0000-0002-5673-8210)
- Magali Lecavalier‐Barsoum (ORCID: https://orcid.org/0000-0002-0068-2764)
- Yujing Zou (ORCID: https://orcid.org/0000-0001-9969-1224)
Institutions
- University of Calgary (CA)
- Jewish General Hospital (CA)
- Computer Algorithms for Medicine (AT)
- McGill University (CA)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1016/j.phro.2025.100793
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00