Pearls and Pitfalls of Intrathecal Amphotericin B Therapy for Refractory Coccidioidal Meningitis in Children: An Illustrative Pediatric Case Series
Intrathecal AmBd remains an important treatment option in pediatric patients with refractory coccidioidal meningitis; however, due to unique administration, challenges may be more of a temporizing measure rather than definitive prolonged therapy. Further experience and multidisciplinary care are needed to reduce mortality.
Authors
- Aria Fallah (ORCID: https://orcid.org/0000-0002-9703-0964)
- Sanchi Malhotra (ORCID: https://orcid.org/0000-0002-2485-3927)
- Paul Krogstad (ORCID: https://orcid.org/0000-0001-6191-6213)
- Royce H. Johnson
- Ishminder Kaur (ORCID: https://orcid.org/0000-0002-1759-8788)
- James McCarty (ORCID: https://orcid.org/0000-0002-7938-3731)
- Kristina Adachi (ORCID: https://orcid.org/0000-0002-5796-2767)
- Lawrence S. Ross
Institutions
- University of California, Los Angeles (US)
- Keck Hospital of USC (US)
- Stanford University (US)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1097/inf.0000000000004888
- Citations
- 4
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.42