Enhanced mitochondrial respiration in peripheral blood mononuclear cells ( <scp>PBMCs</scp> ) from young children with overweight/obesity and insulin resistance
PBMCs from young children with overweight/obesity exhibit adaptations to the metabolic stressors associated with insulin resistance, and PBMC metabolism correlates well with whole-body metabolism.
Authors
- Leanna Delhey (ORCID: https://orcid.org/0000-0003-1301-6952)
- Elisabet Børsheim (ORCID: https://orcid.org/0000-0002-7842-0625)
- Eugénia Carvalho (ORCID: https://orcid.org/0000-0001-6264-3632)
- Reid D. Landes (ORCID: https://orcid.org/0000-0002-6349-0081)
- Shannon Rose (ORCID: https://orcid.org/0000-0003-0595-4367)
- Matthew Cotter
Institutions
- Arkansas Children's Hospital (US)
- University of Tennessee Health Science Center (US)
- University of Michigan (US)
- Arkansas Children's Nutrition Center (US)
- University of Coimbra (PT)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/eci.70090
- Citations
- 2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- U.S. Department of Agriculture
- Arkansas Biosciences Institute
- Children’s Hospital of Wisconsin Research Institute
- European Commission
- National Institutes of Health
- Agricultural Research Service
- HORIZON EUROPE Framework Programme
- Fundação para a Ciência e a Tecnologia
- National Institute of General Medical Sciences