[Paradoxical roles of spontaneous portosystemic shunts and their management strategy in splenectomy with devascularization].

Spontaneous portosystemic shunt (SPSS) is an important pathological feature in the progression of cirrhotic portal hypertension and acts as the body's compensatory mechanism for reducing portal hypertension. Recent research results show that SPSS is an important link in the development of cirrhosis into the decompensated stage and is also the main cause of hepatic encephalopathy after splenectomy combined with devascularization. Therefore, during splenectomy combined with devascularization, it is necessary to decide on treatment measures such as disconnection, flow limitation, or retention of the distal side as a selective shunt channel according to its location and shunt volume.

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Publication Details

Journal
PubMed
Published
2025-05-20
DOI
https://doi.org/10.3760/cma.j.cn501113-20250505-00171
Primary Topic
Liver Disease and Transplantation
Type
article
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article

[Paradoxical roles of spontaneous portosystemic shunts and their management strategy in splenectomy with devascularization].

Youngmin Bu, MingG Tian
1 links
PubMed
Liver Disease and Transplantation
article

[Paradoxical roles of spontaneous portosystemic shunts and their management strategy in splenectomy with devascularization].

Youngmin Bu, MingG Tian
article en

Abstract

Spontaneous portosystemic shunt (SPSS) is an important pathological feature in the progression of cirrhotic portal hypertension and acts as the body's compensatory mechanism for reducing portal hypertension. Recent research results show that SPSS is an important link in the development of cirrhosis into the decompensated stage and is also the main cause of hepatic encephalopathy after splenectomy combined with devascularization. Therefore, during splenectomy combined with devascularization, it is necessary to decide on treatment measures such as disconnection, flow limitation, or retention of the distal side as a selective shunt channel according to its location and shunt volume.

PubMedVol. 33(5)
Ningxia Medical University (CN), Ningxia Medical University General Hospital (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Good health and well-being
Liver Disease and Transplantation
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[Paradoxical roles of spontaneous portosystemic shunts and their management strategy in splenectomy with devascularization]. — Youngmin Bu, MingG Tian · PubMed (2025) | TGRS Research Map | TGRS