Interleukin-6-induced neuroinflammation is exacerbated by subclinical levels of interferon-α
In summary, we demonstrate that subclinical levels of IFN-α can markedly exacerbate IL-6-mediated neurological disease, suggesting that future studies, should consider the combined effects of IL-6 and IFN-α.
Authors
- Pattama Songkhunawej (ORCID: https://orcid.org/0009-0006-0608-485X)
- Markus J. Hofer (ORCID: https://orcid.org/0000-0001-5111-3978)
Institutions
- The University of Sydney (AU)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fnins.2025.1586400
- Citations
- 2
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Australian Government
- University of Sydney