Oral contraceptives and women's preferences for facial masculinity and symmetry: Evidence from a double-blind randomized controlled trial

Several studies have reported that heterosexual women's preferences for male faces vary with hormonal fluctuations over the menstrual cycle and that women tend to prefer more masculine faces during ovulation or when not using hormonal contraceptives. While this has been tested using observational data, we provide the first double-blind randomized controlled study testing if oral contraceptives reduce preferences for facial masculinity and symmetry. Three hundred and forty women were randomized to either oral contraceptives or placebo and their facial preferences were measured at baseline and after 3 months. All analyses follow a pre-registered pre-analysis plan. No statistically significant effect of oral contraceptives on preferences for facial masculinity or facial symmetry was found. In pre-registered exploratory analyses, we further find no statistically significant associations between menstrual cycle phase or hormone levels and facial preferences. These results provide evidence against a causal effect of oral contraceptives on women's preferences for masculine and symmetric faces, although our results should be interpreted cautiously as we only find strong evidence against effect sizes larger than about 0.4 Cohen's d units.

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Publication Details

Journal
Evolution and Human Behavior
Published
2025-06-19
DOI
https://doi.org/10.1016/j.evolhumbehav.2025.106713
Primary Topic
Evolutionary Psychology and Human Behavior
Type
article
Field-Weighted Citation Impact
0.00

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article

Oral contraceptives and women's preferences for facial masculinity and symmetry: Evidence from a double-blind randomized controlled trial

Niklas Zethraeus, Liselott Blomberg, Anna Dreber, Angelica Lindén Hirschberg et al.
Evolution and Human Behavior
Evolutionary Psychology and Human Behavior
article

Oral contraceptives and women's preferences for facial masculinity and symmetry: Evidence from a double-blind randomized controlled trial

Niklas Zethraeus, Liselott Blomberg, Anna Dreber, Angelica Lindén Hirschberg, Eva Ranehill, Coren L. Apicella, Magnus Johannesson, Bo von Schoultz
article en

Abstract

Several studies have reported that heterosexual women's preferences for male faces vary with hormonal fluctuations over the menstrual cycle and that women tend to prefer more masculine faces during ovulation or when not using hormonal contraceptives. While this has been tested using observational data, we provide the first double-blind randomized controlled study testing if oral contraceptives reduce preferences for facial masculinity and symmetry. Three hundred and forty women were randomized to either oral contraceptives or placebo and their facial preferences were measured at baseline and after 3 months. All analyses follow a pre-registered pre-analysis plan. No statistically significant effect of oral contraceptives on preferences for facial masculinity or facial symmetry was found. In pre-registered exploratory analyses, we further find no statistically significant associations between menstrual cycle phase or hormone levels and facial preferences. These results provide evidence against a causal effect of oral contraceptives on women's preferences for masculine and symmetric faces, although our results should be interpreted cautiously as we only find strong evidence against effect sizes larger than about 0.4 Cohen's d units.

Evolution and Human BehaviorVol. 46(5)
Karolinska University Hospital (SE), Stockholm School of Economics (SE), Lund University (SE), Universität Innsbruck (AT), Karolinska Institutet (SE), University of Pennsylvania (US)
Jan Wallanders och Tom Hedelius Stiftelse samt Tore Browaldhs Stiftelse, Forskningsrådet för Arbetsliv och Socialvetenskap, Knut och Alice Wallenbergs Stiftelse, Vetenskapsrådet, Marcus och Amalia Wallenbergs minnesfond
Good health and well-being
Openalex Percentile: Top 86%
Evolutionary Psychology and Human Behavior
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