Sustained Virological Response as a Surrogate Marker for Mortality, Decompensated Cirrhosis, or Hepatocellular Carcinoma in People With Chronic Hepatitis C Virus Infection Treated With Direct-Acting Antivirals: Protocol for a Bayesian and Causal Medi
We will use the German Institute of Quality and Efficiency in Health Care criterion for surrogacy for cancer, with at least 50% of the treatment effect mediated through SVR, but the information will be reported in a way that allows people to interpret the information using their own criteria.
Authors
- Christian Gluud (ORCID: https://orcid.org/0000-0002-8861-0799)
- Kurinchi Selvan Gurusamy (ORCID: https://orcid.org/0000-0002-0313-9134)
Institutions
- Quality of Life Research Center (DK)
- Cochrane (DK)
- University College London (GB)
Publication Details
- Journal
- JMIR Research Protocols
- Published
- 2025-06-19
- DOI
- https://doi.org/10.2196/68113
- Citations
- 1
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 1.32