Sustained Virological Response as a Surrogate Marker for Mortality, Decompensated Cirrhosis, or Hepatocellular Carcinoma in People With Chronic Hepatitis C Virus Infection Treated With Direct-Acting Antivirals: Protocol for a Bayesian and Causal Medi

We will use the German Institute of Quality and Efficiency in Health Care criterion for surrogacy for cancer, with at least 50% of the treatment effect mediated through SVR, but the information will be reported in a way that allows people to interpret the information using their own criteria.

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Publication Details

Journal
JMIR Research Protocols
Published
2025-06-19
DOI
https://doi.org/10.2196/68113
Citations
1
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
1.32
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article

Sustained Virological Response as a Surrogate Marker for Mortality, Decompensated Cirrhosis, or Hepatocellular Carcinoma in People With Chronic Hepatitis C Virus Infection Treated With Direct-Acting Antivirals: Protocol for a Bayesian and Causal Medi

Christian Gluud, Kurinchi Selvan Gurusamy
1 citations
JMIR Research Protocols
Hepatitis C virus research
1.32
article

Sustained Virological Response as a Surrogate Marker for Mortality, Decompensated Cirrhosis, or Hepatocellular Carcinoma in People With Chronic Hepatitis C Virus Infection Treated With Direct-Acting Antivirals: Protocol for a Bayesian and Causal Medi

Christian Gluud, Kurinchi Selvan Gurusamy
article en
1 citations

Abstract

We will use the German Institute of Quality and Efficiency in Health Care criterion for surrogacy for cancer, with at least 50% of the treatment effect mediated through SVR, but the information will be reported in a way that allows people to interpret the information using their own criteria.

JMIR Research ProtocolsVol. 14
Quality of Life Research Center (DK), Cochrane (DK), University College London (GB)
Good health and well-being
Openalex Percentile: Top 19%
Hepatitis C virus research
1.32
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