Pain Reduction Following Eptacog Beta Treatment of Bleeding Episodes in Adolescents and Adults With Haemophilia A or B Complicated by Inhibitors
Pain relief over 24 h was observed with eptacog beta treatment across IDR and age categories. This post hoc study demonstrates that percentage reduction from baseline VAS score influences perception of bleed resolution and can predict treatment outcomes.
Authors
- Giancarlo Castaman (ORCID: https://orcid.org/0000-0003-4973-1317)
- Cedric R.J.R. Hermans (ORCID: https://orcid.org/0000-0001-5429-8437)
- Michael Recht (ORCID: https://orcid.org/0000-0002-2805-1016)
- Steven W. Pipe (ORCID: https://orcid.org/0000-0003-2558-2089)
- Craig M. Kessler (ORCID: https://orcid.org/0000-0003-0599-5724)
- Tyler W. Buckner (ORCID: https://orcid.org/0000-0003-1954-4385)
- Víctor Jiménez‐Yuste (ORCID: https://orcid.org/0000-0003-3937-3499)
- Allison P. Wheeler (ORCID: https://orcid.org/0000-0003-3967-4873)
- Leonard A. Valentino (ORCID: https://orcid.org/0000-0002-7927-6418)
- Johannes Oldenburg (ORCID: https://orcid.org/0000-0002-1585-4100)
- Wolfgang Miesbach (ORCID: https://orcid.org/0000-0002-4506-0061)
- Johnny Ndoni Mahlangu (ORCID: https://orcid.org/0000-0001-5781-7669)
Institutions
- Goethe University Frankfurt (DE)
- Rush University Medical Center (US)
- Cliniques Universitaires Saint-Luc (BE)
- University of Bonn (DE)
- Georgetown University (US)
- University of the Witwatersrand (ZA)
- University of Washington (US)
- University of Michigan (US)
- Hospital Universitario La Paz (ES)
- MedStar Georgetown University Hospital (US)
- Yale University (US)
- Michigan United (US)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- University Hospital Frankfurt (DE)
- Washington Center (US)
- UCLouvain (BE)
Publication Details
- Journal
- Haemophilia
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1111/hae.70077
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00