Human serum albumin-based KBiF4@HSA nanoclusters for dual-energy computed tomography and glutathione-scavenging radiotherapy of breast cancer
This study presents a novel approach for the development of biocompatible DECT contrast agents and radiosensitizers, offering a promising strategy to enhance breast cancer diagnosis and treatment. However, the efficacy of this approach needs to be further validated across diverse breast cancer subtypes to ensure its broad applicability, which emphasizes the necessity for continued research to fully translate this innovative technology into clinical practice.
Authors
- Defan Yao (ORCID: https://orcid.org/0000-0002-8870-3637)
- Zhenghai Lu
- Ningxin Yang
- Huanhuan Liu
- Yi Huang (ORCID: https://orcid.org/0000-0001-7774-1024)
- Yanhong Chen (ORCID: https://orcid.org/0000-0002-9965-5773)
- Jingjing Hu (ORCID: https://orcid.org/0000-0001-5083-7114)
- Dengbin Wang (ORCID: https://orcid.org/0000-0001-9529-4870)
- Weixi Huang
- Chunting Wang
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai University of Sport (CN)
- XinHua Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1186/s12951-025-03530-8
- Citations
- 2
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- Shanghai Rising-Star Program