Therapeutic efficacy of 5-alkylresorcinol on progression of colorectal cancer by activating HCLS1 and suppressing TLR4/MYD88/NF-κB signaling
These findings suggest that 5ARs may exert their anti-cancer effects by activating HCLS1 and suppressing TLR4/MYD88/NF-κB signaling, thus offering a potential new therapeutic strategy for CRC.
Authors
- Fan Wan (ORCID: https://orcid.org/0000-0002-3749-3887)
- Heng Li (ORCID: https://orcid.org/0000-0002-6666-0277)
- Jian Wang (ORCID: https://orcid.org/0000-0002-9482-5227)
- Jun Yang (ORCID: https://orcid.org/0000-0001-6085-9245)
- Chun Yang (ORCID: https://orcid.org/0000-0001-6148-0237)
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1186/s40001-025-02775-1
- Citations
- 1
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Ningxia Province