Platelet/high-density lipoprotein cholesterol ratio as a biomarker of depression in individuals with chronic opioid use
Elevated PHR is independently associated with depression in individuals with chronic opioid use, suggesting its potential as a biomarker for identifying at-risk populations. The findings underscore the need to address systemic inflammation and lipid dysregulation as part of integrated mental health care for opioid users.
Authors
- Shan Chen (ORCID: https://orcid.org/0000-0001-7613-3940)
- Hong Chen (ORCID: https://orcid.org/0000-0003-4997-7368)
- Qin Li (ORCID: https://orcid.org/0000-0002-3907-3245)
- Chengxiang Liu (ORCID: https://orcid.org/0009-0004-8009-8649)
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fpsyt.2025.1582449
- Primary Topic
- Cardiac Health and Mental Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00