Subcutaneous adipose tissue gene transcripts associated with progressive myosteatosis in persons with HIV
A subset of SAT gene transcripts is associated with changes in skeletal muscle density and area over time, suggesting interventions to modulate SAT immune activity or improve lipid handling may hold therapeutic potential to slow the progression of myosteatosis and sarcopenia in PWH.
Authors
- Oliver Zhao (ORCID: https://orcid.org/0000-0001-7668-7708)
- J. Jeffrey Carr (ORCID: https://orcid.org/0000-0002-4398-8237)
- Sangeeta Nair (ORCID: https://orcid.org/0000-0002-9725-9195)
- Samuel Bailin (ORCID: https://orcid.org/0000-0003-4990-1013)
- Heidi J. Silver (ORCID: https://orcid.org/0000-0003-2237-4903)
- Curtis L. Gabriel (ORCID: https://orcid.org/0000-0002-1611-3136)
- James Greg Terry (ORCID: https://orcid.org/0000-0001-6659-3441)
- Celestine N. Wanjalla (ORCID: https://orcid.org/0000-0001-9159-5414)
- Mona Mashayekhi (ORCID: https://orcid.org/0000-0003-0331-2395)
- John R. Koethe (ORCID: https://orcid.org/0000-0001-6490-6942)
- Fei Ye (ORCID: https://orcid.org/0000-0001-6472-5076)
- Qi Liu (ORCID: https://orcid.org/0000-0002-6698-8379)
- Run Fan
Institutions
- Vanderbilt University (US)
- VA Tennessee Valley Healthcare System (US)
- Office of Infectious Diseases (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- AIDS
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1097/qad.0000000000004264
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00