Ultra-fast line-field swept source scanning optical coherence elastography
The drawbacks of repeated excitations and long imaging time in wave-based optical coherence elastography limited its application in ophthalmology. In this study, we put forward a swept source scanning optical coherence elastography (SSS-OCE) system based on the wavelength-dependence scanning technique. A dispersive element was employed to achieve ultra-fast line scanning from swept light source. Through a series of experiments on agar phantoms with varying concentrations, in situ porcine corneas under different intraocular pressures, and human eyes in vivo, we have demonstrated that SSS-OCE has the capability to rapidly evaluate the elasticity of ocular tissues in vivo with single excitation and offers the advantages of a simple structure and short measurement time.
Authors
- J. R. Ren (ORCID: https://orcid.org/0000-0002-0166-4445)
- Xinlu Cheng (ORCID: https://orcid.org/0000-0002-2661-556X)
- Xin Wei (ORCID: https://orcid.org/0000-0001-8865-1956)
- Dexi Zhu (ORCID: https://orcid.org/0000-0001-5553-2088)
- K. Y. Shen (ORCID: https://orcid.org/0009-0008-9792-5654)
- Meixiao Shen (ORCID: https://orcid.org/0000-0002-5237-267X)
- Qi Huang (ORCID: https://orcid.org/0000-0002-8853-946X)
- Xingyu Zhou (ORCID: https://orcid.org/0009-0005-7024-7011)
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Hormuud University (SO)
- Sohu (China) (CN)
Publication Details
- Journal
- Biomedical Optics Express
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1364/boe.566466
- Citations
- 3
- Primary Topic
- Optical Coherence Tomography Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province