A Longitudinal and Reproducible Anti-Coactivation Pattern Between the Cerebellum and the Ventral Tegmental Area Is Related to Apathy in Schizophrenia
Reduced cerebellum-VTA anti-coactivation is a reproducible neural marker of apathy in SZ, highlighting its potential as a therapeutic target.
Authors
- Dimitri Van De Ville (ORCID: https://orcid.org/0000-0002-2879-3861)
- Indrit Bègue (ORCID: https://orcid.org/0000-0001-5350-4454)
- Stefan Kaiser (ORCID: https://orcid.org/0000-0002-3013-2034)
- Fares Alouf
- Thomas A. W. Bolton (ORCID: https://orcid.org/0000-0002-2081-4031)
- Stéphan Eliez (ORCID: https://orcid.org/0000-0002-8269-3028)
- Fabien Carruzzo (ORCID: https://orcid.org/0000-0003-2386-3389)
- Mariia Kaliuzhna (ORCID: https://orcid.org/0000-0002-0954-961X)
- Farnaz Delavari (ORCID: https://orcid.org/0000-0003-2990-4372)
- Tal Geffen
- Florian Schlagenhauf (ORCID: https://orcid.org/0000-0001-8340-5027)
- Teresa Katthagen (ORCID: https://orcid.org/0000-0002-7537-4192)
- Noémie Kuenzi (ORCID: https://orcid.org/0000-0003-1368-167X)
- Jade Awada
Institutions
- University of Geneva (CH)
- University Hospital of Geneva (CH)
- Cognitive Neuroimaging Lab (FR)
- École Polytechnique Fédérale de Lausanne (CH)
- Geneva College (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Biological Psychiatry
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.biopsych.2025.06.009
- Citations
- 4
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Fondation Leenaards
- Hôpitaux Universitaires de Genève