Research Progress in Imaging Diagnosis of Bone Metastasis of Prostate Cancer

前列腺癌是全球成年男性发病率最高的恶性肿瘤之一，约70%的晚期患者都会发生骨转移，从而导致一系列骨骼相关事件，这降低了患者的生活质量并增加了死亡风险。因此，前列腺癌及前列腺癌骨转移的早期诊断和预测至关重要，这对协助临床医生判断病情和选择治疗方案有较高的临床意义。本文从前列腺癌骨转移发生的机制和影像学检查技术等方面进行总结，重点介绍了单光子发射计算机断层显像、CT/X线、MRI扫描、正电子发射断层扫描/计算机断层扫描、超声及影像组学在前列腺癌骨转移早期诊断中的应用价值。Prostate cancer is one of the malignant tumors with the highest incidence among adult males in the world. About 70% of patients in advanced stage will have bone metastasis, which will lead to a series of bone-related events, which will reduce the quality of life of patients and increase the risk of death. Therefore, early diagnosis and prediction of prostate cancer and bone metastasis of prostate cancer are very important. It is of high clinical significance to assist clinicians to judge the condition and choose the treatment plan. In this paper, the mechanism and imaging techniques of bone metastasis of prostate cancer are summarized, and the application values of single photon emission computed tomography, CT/X-ray, MRI scanning, positron emission tomography/computed tomography, ultrasound and imaging in the early diagnosis of bone metastasis of prostate cancer are emphatically introduced.