Antibiotic Usage During Surgery may be Correlated With Survival in Radically Resected Non-Small-Cell Lung Cancer Patients

This study, for the first time, explored the prognostic value of ATB use during surgery in NSCLC patients and revealed that multiple types of ATBs may be associated with OS in patients with stage I to III disease. Notably, patients treated with <i>fluoroquinolones</i> may have inferior outcomes than those without ATB use. However, multiple types of ATBs were not validated as independent risk factors for OS. These results suggest that the use of ATBs during surgery in early-stage NSCLC is generally safe; however, caution should be taken when selecting ATB types. Multiple ATB types should be avoided, and some specific ATB types, such as <i>fluoroquinolones</i>, should not be administered. Nonetheless, owing to the limited sample sizes, future studies are needed to validate our results.