Obesity and cervical intraepithelial neoplasia: regulation of mitochondrial energy metabolism via the Kisspeptin/GPR54 signaling pathway
The Kisspeptin/GPR54 signaling pathway enhances mitochondrial energy metabolism, promoting obesity-related CIN grade. These findings provide a potential molecular mechanism linking obesity to CC and suggest new therapeutic targets.
Authors
- Peipei Li (ORCID: https://orcid.org/0000-0001-7715-9886)
- Feifei Ni (ORCID: https://orcid.org/0000-0002-0369-5595)
- Haizhen He (ORCID: https://orcid.org/0009-0009-0923-6267)
- Yuanyuan Chen (ORCID: https://orcid.org/0000-0002-6142-5913)
- Ye Yan (ORCID: https://orcid.org/0000-0003-0847-561X)
- Jiajia Pan (ORCID: https://orcid.org/0000-0003-3829-6671)
Institutions
- Wenzhou Medical University (CN)
- Wenzhou City People's Hospital (CN)
Publication Details
- Journal
- Cancer & Metabolism
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1186/s40170-025-00398-y
- Citations
- 1
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Wenzhou Municipal Science and Technology Bureau