The Platelet-to-Lymphocyte Ratio (PLR) as a Non-Invasive Biomarker for Cervical Malignancy in Conization Patients

The PLR cutoff of 7.7 was associated with HPV positivity, while a higher cutoff of 11.93 was identified for predicting invasive cervical cancer. These findings support that preoperative PLR is a non-invasive, clinically relevant marker correlated with lesion severity, offering potential for preoperative risk stratification, particularly where advanced diagnostics are limited.

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Publication Details

Journal
Life
Published
2025-06-18
DOI
https://doi.org/10.3390/life15060971
Citations
3
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
3.14
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article

The Platelet-to-Lymphocyte Ratio (PLR) as a Non-Invasive Biomarker for Cervical Malignancy in Conization Patients

Márton Keszthelyi, Attila Keszthelyi, Nándor Ács, Petra Merkely et al.
3 citations
Life
Inflammatory Biomarkers in Disease Prognosis
3.14
article

The Platelet-to-Lymphocyte Ratio (PLR) as a Non-Invasive Biomarker for Cervical Malignancy in Conization Patients

Márton Keszthelyi, Attila Keszthelyi, Nándor Ács, Petra Merkely, V. Szabó, Lotti Lőczi, Balázs Lintner, Szabolcs Várbı́ró, Richárd Tóth, Zsófia Tóth, Balázs Vida, Barbara Sebők
article en
3 citations

Abstract

The PLR cutoff of 7.7 was associated with HPV positivity, while a higher cutoff of 11.93 was identified for predicting invasive cervical cancer. These findings support that preoperative PLR is a non-invasive, clinically relevant marker correlated with lesion severity, offering potential for preoperative risk stratification, particularly where advanced diagnostics are limited.

LifeVol. 15(6)
Semmelweis University (HU), University of Szeged (HU)
Openalex Percentile: Top 8%
Inflammatory Biomarkers in Disease Prognosis
3.14
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