A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report

PurposeTo describe a case of Acute Syphilitic Posterior Placoid Chorio-retinitis characterized by a peculiar optical coherence tomography (OCT) finding.MethodsThe patient underwent comprehensive ophthalmic examination, including ultra-wide field fundus photography, fluorescein angiography, and spectral-domain OCT.ResultsThis finding was characterized by hyper-reflective lesions located between the retinal pigment epithelium and the outer plexiform layer involving almost the outer nuclear layer.ConclusionWe suggest that this finding could be a sign of outer retina inflammation related to the Syphilis infection and may be helpful in the early diagnosis of ASPCC.

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Publication Details

Journal
European Journal of Ophthalmology
Published
2025-06-18
DOI
https://doi.org/10.1177/11206721251351066
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
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OCT
article

A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report

Giuseppe Querques, Federico Rissotto, Francesco Bandello, Elisabetta Miserocchi et al.
European Journal of Ophthalmology
Syphilis Diagnosis and Treatment
article

A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report

Giuseppe Querques, Federico Rissotto, Francesco Bandello, Elisabetta Miserocchi, Riccardo Sacconi, Gloria Oldoni, Federico Beretta
article en

Abstract

PurposeTo describe a case of Acute Syphilitic Posterior Placoid Chorio-retinitis characterized by a peculiar optical coherence tomography (OCT) finding.MethodsThe patient underwent comprehensive ophthalmic examination, including ultra-wide field fundus photography, fluorescein angiography, and spectral-domain OCT.ResultsThis finding was characterized by hyper-reflective lesions located between the retinal pigment epithelium and the outer plexiform layer involving almost the outer nuclear layer.ConclusionWe suggest that this finding could be a sign of outer retina inflammation related to the Syphilis infection and may be helpful in the early diagnosis of ASPCC.

European Journal of OphthalmologyVol. 35(6)
Vita-Salute San Raffaele University (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Good health and well-being
Openalex Percentile: Top 81%
Syphilis Diagnosis and Treatment
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A novel finding in the diagnosis of acute syphilitic posterior placoid chorioretinitis: A case report — Giuseppe Querques, Federico Rissotto, et al. · European Journal of Ophthalmology (2025) | TGRS Research Map | TGRS