Research Progress on the Active Components and Clinical Application of <i>Polygonum </i><i>cuspidatum</i>

虎杖作为传统中药，中医认为其具有利胆退黄、清热解毒、散瘀止痛、泻热通便、止咳化痰之功效。现代研究表明其有效成分复杂，包括二苯乙烯类、蒽醌类、黄酮类、苯丙素类等，具有抗炎、降低血管通透性、保护血管内皮、抗癌等作用，作用于多个器官，起到保护心肌、拮抗哮喘、抗肺水肿、抑制肝纤维化、保护肾小管上皮细胞等功效，可广泛用于治疗炎症、病毒性、细菌感染性及神经退行性等疾病，具有极高的临床药理价值。As a traditional Chinese medicine, Polygonum cuspidatum is believed to have the effects of promoting bile flow, reducing jaundice, clearing heat and detoxifying, dispersing blood stasis and relieving pain, clearing heat and promoting bowel movements, and relieving cough and phlegm. Modern research has shown that its active ingredients are complex, including stilbenes, anthraquinones, flavonoids, phenylpropanoids, etc. It has anti-inflammatory, vascular permeability reducing, endothelial protective, anti-cancer and other effects. It acts on multiple organs, protecting the heart muscle, antagonizing asthma, anti pulmonary edema, inhibiting liver fibrosis, protecting renal tubular epithelial cells, etc. It can be widely used to treat inflammation, viral, bacterial infectious and neurodegenerative diseases, and has high clinical pharmacological value.