Comprehensive clinical and metabolomics profiling of COVID-19 Mexican patients across three epidemiological waves
Among the 21 classes of compounds evaluated in this study, amino acids and lipids were the most dysregulated when comparing age, sex, comorbidities, vaccination status, and the different epidemiological waves. This is the most comprehensive analysis in Mexico providing absolute quantitative data for 529 metabolites and lipids measured in hospitalized COVID-19 patients, which could be used to monitor their metabolic status and clinical outcomes associated with COVID-19 infection or with long COVID syndrome.
Authors
- David S. Wishart (ORCID: https://orcid.org/0000-0002-3207-2434)
- Juan Carlos Borrego (ORCID: https://orcid.org/0000-0001-5208-3264)
- Yamilé López‐Hernández (ORCID: https://orcid.org/0000-0002-1068-603X)
- Sergio Hugo Sánchez Rodríguez (ORCID: https://orcid.org/0000-0002-7764-7211)
- Alanne T. Nunes (ORCID: https://orcid.org/0000-0001-6246-8934)
- Jesús Adrián López (ORCID: https://orcid.org/0000-0001-8012-7041)
- Joel Monárrez‐Espino (ORCID: https://orcid.org/0000-0002-0695-5356)
- Juan José Oropeza-Valdez (ORCID: https://orcid.org/0000-0003-1093-9970)
- David Alejandro García López (ORCID: https://orcid.org/0000-0003-2064-1959)
- Claudia Torres-Calzada (ORCID: https://orcid.org/0000-0001-9372-7230)
- Blanca Rodríguez (ORCID: https://orcid.org/0000-0001-6361-3339)
- Jiamin Zheng (ORCID: https://orcid.org/0000-0002-6120-7035)
- Rupasri Mandal
Institutions
- Autonomous University of Chihuahua (MX)
- University of Alberta (CA)
- Universidad Autónoma de la Ciudad de México (MX)
- Universidade de São Paulo (BR)
- Hospital General De Zona (MX)
- Universidad Autónoma de Zacatecas "Francisco García Salinas" (MX)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fmolb.2025.1607583
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61