A Slow Hydrogen Sulfide Donor GYY-4137 Partially Improves Vascular Function in Spontaneously Hypertensive Rats Fed a High-Fat Diet
A slow H<sub>2</sub>S-releasing donor could partially ameliorate the metabolic changes induced by increased fat intake during essential hypertension and trigger beneficial vasoactive effects associated with the NO signaling restoration and suppression of inflammation.
Authors
- Andrea Berenyiová (ORCID: https://orcid.org/0000-0003-3108-238X)
- Andrej Barta
- Basak G. Aydemir
- Soňa Čačányiová (ORCID: https://orcid.org/0000-0003-0483-7468)
- Martina Cebová (ORCID: https://orcid.org/0000-0003-0132-670X)
- John Henderson (ORCID: https://orcid.org/0000-0001-8546-1655)
Institutions
- University of Copenhagen (DK)
- Slovak Academy of Sciences (SK)
- Novo Nordisk Foundation (DK)
- Centre of Experimental Medicine of the Slovak Academy of Sciences (SK)
- Institute of Normal and Pathological Physiology of the Slovak Academy of Sciences (SK)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Pathophysiology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3390/pathophysiology32020027
- Citations
- 2
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 2.22
Funders
- Agentúra na Podporu Výskumu a Vývoja