Deformation of brain in normal pressure hydrocephalus is more readily associated with slow vasomotion rather than heartbeat related pulsations of intracranial pressure
Mainly SLOW showed correlations with the morphological imaging features of iNPH. SLOW is influenced by vasomotion and intracranial compliance. This study suggests that the magnitude of ICP slow wave activity, but not ICP pulse component is related to the size of brain ventricles and DESH in iNPH.
Authors
- Matthias Jaeger (ORCID: https://orcid.org/0000-0002-7500-9160)
- Ronald T. Murambi
- Craig R. Vonhoff (ORCID: https://orcid.org/0000-0001-6505-5967)
- Magdalena Kasprowicz (ORCID: https://orcid.org/0000-0002-2271-7737)
- Marek Czosnyka (ORCID: https://orcid.org/0000-0003-2446-8006)
- Zofia Czosnyka
- Henora Chour
Institutions
- Warsaw University of Technology (PL)
- Wrocław University of Science and Technology (PL)
- University of Wollongong (AU)
- University of Cambridge (GB)
- Wollongong Hospital (AU)
- Addenbrooke's Hospital (GB)
- AGH University of Krakow (PL)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1186/s12987-025-00670-9
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00