Photoreceptor cone loss is associated with decreased deep retinal vessel density and impaired retinal sensitivity in high myopia
Our findings demonstrate that impaired DCP perfusion independently predicts cone loss in non-pathological HM, independent of axial elongation. RS impairment is associated with cone loss, MEZ thinning and DCP hypoperfusion, indicating synergistic microvascular and structural damage in HM-related vision impairment.
Authors
- Kunke Li
- Dong Fang (ORCID: https://orcid.org/0000-0003-4954-5493)
- Y.H. Diao
- Ting Xie (ORCID: https://orcid.org/0000-0002-8369-1067)
- Wangting Li (ORCID: https://orcid.org/0000-0001-7070-5768)
- Zhenhua Zou (ORCID: https://orcid.org/0000-0002-1682-0893)
- Shaochong Zhang (ORCID: https://orcid.org/0000-0002-1911-6930)
- Lujia Feng (ORCID: https://orcid.org/0000-0002-5046-7544)
- Pengfeng Li
- Jia Liang (ORCID: https://orcid.org/0000-0002-1883-6442)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-6531-0451)
- Lu Chen (ORCID: https://orcid.org/0000-0003-1141-8288)
- Huiyan Zheng
- Xiangcheng Tang (ORCID: https://orcid.org/0009-0001-2338-3388)
- Changfeng Pan
- Zonghui Yan
- Xiangqing Hei
Institutions
- Southern Medical University Shenzhen Hospital (CN)
- Wuhu Hit Robot Technology Research Institute (CN)
- He Eye Hospital (CN)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1136/bjo-2024-326609
- Citations
- 3
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.12
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province