Evaluation of pH, free available chlorine and tissue dissolution property of solid dosage chlorine releasing agents for root canal irrigation based on contact time – An in vitro study

Aim: The aim of the study was to evaluate the pH, free available chlorine (FAC), and tissue dissolution property of various chlorine-releasing solutions prepared from predosed tablets based on the period since the preparation of the solution. Methods: Groups 1–3 are the study solutions prepared by dissolving 2.5 g of the chemical in powder form in 100 mL distilled water to obtain a 2.5% solution. The control solution is the commercially available 2.5% sodium hypochlorite (NaOCl) solution. The solutions were freshly prepared and used immediately before testing each aspect of the study. (1) Group 1: 2.5% calcium hypochlorite, (2) Group 2: 2.5% chlorine dioxide (ClO 2 ), (3) Group 3: 2.5% sodium dichloroisocyanurate, (4) Group 4: 2.5% NaOCl, (5) Group 5: saline (negative control). Results: The comparison of pH, FAC, and tissue dissolution property between NaOCl and ClO 2 was statistically nonsignificant, whereas the comparison was significant with respect to the other test solutions. Conclusion: ClO 2 shows more similarity to NaOCl as an irrigant used for root canal treatments. There was not any significant difference between ClO 2 and NaOCl in its FAC and tissue dissolution properties.