Metabolomics Profiling of Epicardial Adipose Tissue: MESA and the Rotterdam Study
From >20 000 metabolomic features, 1,5-anhydrosorbitol, glycoproteins, phospholipids, and atherogenic dyslipidemia markers emerged as significant markers of EAT. Further investigation is warranted to determine whether nuclear magnetic resonance-based metabolic profiling can improve EAT detection with implications for cardiometabolic health.
Authors
- Philip Greenland (ORCID: https://orcid.org/0000-0002-6327-2439)
- Gianluca Iacobellis (ORCID: https://orcid.org/0000-0001-7888-9530)
- Jeffrey J. Goldberger (ORCID: https://orcid.org/0000-0001-9802-1851)
- Gonçalo Graça (ORCID: https://orcid.org/0000-0002-0876-3876)
- Anastasios Lymperopoulos (ORCID: https://orcid.org/0000-0001-9817-6319)
- Mohsen Ghanbari (ORCID: https://orcid.org/0000-0002-9476-7143)
- Maryam Kavousi (ORCID: https://orcid.org/0000-0001-5976-6519)
- Ian J. Neeland (ORCID: https://orcid.org/0000-0003-2831-3618)
- Ali Farzaneh (ORCID: https://orcid.org/0009-0005-4496-2863)
- Daniël Bos (ORCID: https://orcid.org/0000-0001-8979-2603)
- Fang Zhu (ORCID: https://orcid.org/0000-0002-0449-6766)
Institutions
- University of Miami (US)
- Nova Southeastern University (US)
- University Hospitals of Cleveland (US)
- Erasmus MC (NL)
- Imperial College London (GB)
- Case Western Reserve University (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1161/jaha.124.039750
- Citations
- 4
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 5.55