Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree‐Based Dimensionality Reduction
Our findings challenge the current paradigm, highlighting the potential for these phenogroups to enhance cardiac resynchronization therapy patient selection for subjects with LBBB and guide investigation and follow-up strategies for subjects with higher risk right bundle-branch block.
Authors
- Joseph Barker (ORCID: https://orcid.org/0000-0002-5483-9608)
- Konstantinos Patlatzoglou (ORCID: https://orcid.org/0000-0002-5888-8490)
- Libor Pastika (ORCID: https://orcid.org/0000-0001-6892-6553)
- Ahran Arnold (ORCID: https://orcid.org/0000-0002-7597-0170)
- Ewa Sieliwończyk (ORCID: https://orcid.org/0000-0002-8603-7044)
- Daniel B. Kramer (ORCID: https://orcid.org/0000-0003-4241-3586)
- Arunashis Sau (ORCID: https://orcid.org/0000-0002-0204-7078)
- Kenneth C. Bilchick (ORCID: https://orcid.org/0000-0002-5188-3603)
- Derek Bivona (ORCID: https://orcid.org/0000-0002-4759-1157)
- Declan P. O’Regan (ORCID: https://orcid.org/0000-0002-0691-0270)
- Lara Curran (ORCID: https://orcid.org/0000-0003-1260-3741)
- Zachary I. Whinnett (ORCID: https://orcid.org/0000-0002-2775-5126)
- Fu Siong Ng (ORCID: https://orcid.org/0000-0002-8681-4368)
- Jonathan W. Waks (ORCID: https://orcid.org/0000-0001-5560-5638)
- Mehak Gurnani (ORCID: https://orcid.org/0009-0003-9228-2518)
- Nicholas S. Peters (ORCID: https://orcid.org/0000-0002-3581-8078)
- Boroumand Zeidaabadi (ORCID: https://orcid.org/0009-0004-0025-9896)
- Paolo Inglese (ORCID: https://orcid.org/0000-0001-6179-9643)
Institutions
- Harvard University (US)
- University of Antwerp (BE)
- Imperial College Healthcare NHS Trust (GB)
- University of Virginia Health System (US)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- Italian Institute of Technology (IT)
- Lung Institute (US)
- Antwerp University Hospital (BE)
- Imperial College London (GB)
- University of Virginia (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1161/jaha.124.040814
- Citations
- 1
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39