There is no transfer of mitochondria from donor hematopoietic cells to recipient mesenchymal stromal cells after allogeneic hematopoietic stem cells transplantation in humans
The data show that there is no mitochondrial transfer from donor hematopoietic stem and progenitor cells to recipient mesenchymal stromal cells after transplantation. Thus, the results indicate that one cannot count on improved mesenchymal stromal cell metabolism due to mitochondrial transfer. It is necessary to look for other ways to restore the stromal microenvironment.
Authors
- Н. И. Дризе (ORCID: https://orcid.org/0000-0002-7150-0403)
- Е. Н. Паровичникова (ORCID: https://orcid.org/0000-0001-6177-3566)
- N. V. Sats (ORCID: https://orcid.org/0000-0002-1559-9381)
- В. Л. Сурин (ORCID: https://orcid.org/0000-0002-1890-4492)
- Larisa A. Kuzmina (ORCID: https://orcid.org/0000-0001-6201-6276)
- К. А. Никифорова (ORCID: https://orcid.org/0000-0002-4119-7175)
- Н. М. Капранов (ORCID: https://orcid.org/0000-0002-6512-910X)
- Luisa Karaseva
- Н. А. Петинати (ORCID: https://orcid.org/0000-0001-6591-3183)
- Olga S. Pokrovskaya (ORCID: https://orcid.org/0000-0002-8657-4990)
- Т В Абрамова (ORCID: https://orcid.org/0000-0003-3163-4930)
- Aleksandra Sadovskaya (ORCID: https://orcid.org/0000-0002-0221-9351)
Institutions
- Lomonosov Moscow State University (RU)
- Endocrinology Research Center (RU)
Publication Details
- Journal
- Hematology Transfusion and Cell Therapy
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.htct.2025.103859
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00