Human mastadenovirus pneumonia in two immunocompetent patients
These two cases demonstrated a remarkably similar clinical and histopathological profile, characterized by chronic granulomatous lung inflammation. The findings suggest a prolonged inflammatory response leading to persistent tissue damage. Our observations highlight the potential of hAdV-B to cause chronic pneumonia even in otherwise healthy individuals.
Authors
- Spasenija Savic Prince (ORCID: https://orcid.org/0000-0002-4065-5111)
- Lucas Boeck (ORCID: https://orcid.org/0000-0002-1442-9073)
- Salome Hosch (ORCID: https://orcid.org/0000-0001-9290-3589)
- Baptiste Hamelin (ORCID: https://orcid.org/0000-0001-8928-8597)
- Christopher M. Field
- Albert Heim (ORCID: https://orcid.org/0000-0002-9447-1561)
- Kirsten D. Mertz (ORCID: https://orcid.org/0000-0002-3074-6925)
- Karoline Leuzinger (ORCID: https://orcid.org/0000-0002-5654-9356)
- Tanja Gradistanac
- Jasmin D. Haslbauer (ORCID: https://orcid.org/0000-0001-7609-8612)
- Peter M. Keller (ORCID: https://orcid.org/0000-0002-2890-5384)
- Anita E Gander
Institutions
- University of Basel (CH)
- University Hospital of Basel (CH)
- Medizinische Hochschule Hannover (DE)
- Kantonsspital Graubünden (CH)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1186/s12985-025-02823-6
- Citations
- 1
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Universität Basel