Dopaminergic Modulation of Conscientiousness: DRD2 rs1799732 and Personality Traits in Elite Mixed Martial Arts Athletes

These findings suggest that the DRD2 promoter polymorphism rs1799732 moderates the expression of Conscientiousness, particularly under the structured and demanding conditions experienced by elite athletes. Our results support a gene × environment interaction model, highlighting the importance of considering genetic predispositions in high-performance environments. These insights may inform personalised psychological support strategies tailored to athletes' genetic profiles, enhancing motivation, self-regulation and long-term athletic development.

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Publication Details

Journal
Genes
Published
2025-06-18
DOI
https://doi.org/10.3390/genes16060720
Citations
5
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
4.55

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article

Dopaminergic Modulation of Conscientiousness: DRD2 rs1799732 and Personality Traits in Elite Mixed Martial Arts Athletes

Jolanta Chmielowiec, Jolanta Masiak, Anna Grzywacz, Milena Lachowicz et al.
5 citations
Genes
Neurotransmitter Receptor Influence on Behavior
4.55
article

Dopaminergic Modulation of Conscientiousness: DRD2 rs1799732 and Personality Traits in Elite Mixed Martial Arts Athletes

Jolanta Chmielowiec, Jolanta Masiak, Anna Grzywacz, Milena Lachowicz, Aleksandra Suchanecka, Krzysztof Chmielowiec, Remigiusz Recław, Kinga Łosińska
article en
5 citations

Abstract

These findings suggest that the DRD2 promoter polymorphism rs1799732 moderates the expression of Conscientiousness, particularly under the structured and demanding conditions experienced by elite athletes. Our results support a gene × environment interaction model, highlighting the importance of considering genetic predispositions in high-performance environments. These insights may inform personalised psychological support strategies tailored to athletes' genetic profiles, enhancing motivation, self-regulation and long-term athletic development.

GenesVol. 16(6)
Medical University of Lublin (PL), Gdansk University of Physical Education and Sport (PL), University of Zielona Góra (PL), Gdańsk Medical University (PL), Pomeranian Medical University (PL)
Narodowe Centrum Nauki
Openalex Percentile: Top 5%
Neurotransmitter Receptor Influence on Behavior
4.55
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Dopaminergic Modulation of Conscientiousness: DRD2 rs1799732 and Personality Traits in Elite Mixed Martial Arts Athletes — Jolanta Chmielowiec, Jolanta Masiak, et al. · Genes (2025) | TGRS Research Map | TGRS