Prediction of Antithrombin Activity and Bioavailability of a SyntheticPeptide Using a Decision Tree Algorithm

Employing a decision tree method to assess the antithrombin activity and bioavailability of peptides can facilitate the development of effective oral peptides, hence minimizing the development time and the quantity of in vitro and in vivo studies required to validate efficacy.

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Publication Details

Journal
Current Protein and Peptide Science
Published
2025-06-16
DOI
https://doi.org/10.2174/0113892037356348250523031542
Primary Topic
Protein Hydrolysis and Bioactive Peptides
Type
article
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article

Prediction of Antithrombin Activity and Bioavailability of a SyntheticPeptide Using a Decision Tree Algorithm

Olga Babich, Stanislav A. Sukhikh, С.Л. Тихонов, Н. В. Тихонова et al.
Current Protein and Peptide Science
Protein Hydrolysis and Bioactive Peptides
article

Prediction of Antithrombin Activity and Bioavailability of a SyntheticPeptide Using a Decision Tree Algorithm

Olga Babich, Stanislav A. Sukhikh, С.Л. Тихонов, Н. В. Тихонова, Irina M. Chernukha
article en

Abstract

Employing a decision tree method to assess the antithrombin activity and bioavailability of peptides can facilitate the development of effective oral peptides, hence minimizing the development time and the quantity of in vitro and in vivo studies required to validate efficacy.

Current Protein and Peptide ScienceVol. 26
Immanuel Kant Baltic Federal University (RU), Ural State Forestry Engineering University (RU), Ural State Agrarian University (RU), All-Russian Scientific Research Institute of Refrigeration Industry (RU)
Good health and well-being
Openalex Percentile: Top 87%
Protein Hydrolysis and Bioactive Peptides
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