Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance
This study clarifies the role of the CLU-BCL2L1 axis in promoting glioma migration and proliferation both <i>in vitro</i> and <i>in vivo</i>. It suggests that targeting this pathway may be a promising therapeutic strategy for glioma.
Authors
- Yifan Xiao (ORCID: https://orcid.org/0000-0001-5049-0288)
- Yiyuan Xia (ORCID: https://orcid.org/0000-0001-7833-0497)
- Qi Xiong (ORCID: https://orcid.org/0000-0002-7782-6498)
- Xiji Shu
- Wenli Huang (ORCID: https://orcid.org/0000-0002-8438-5539)
- Hongyan Zhou (ORCID: https://orcid.org/0009-0007-2118-5365)
- Shiyu Yuan (ORCID: https://orcid.org/0009-0000-2842-7354)
- Yuran Gui
- Xin Liu (ORCID: https://orcid.org/0000-0003-3256-2940)
- Yibo Zhang (ORCID: https://orcid.org/0000-0001-5542-2495)
- Xiaochuan Wang (ORCID: https://orcid.org/0000-0001-8207-0042)
- Qingqing Xu
- Mingshan Pi (ORCID: https://orcid.org/0009-0008-8333-5653)
Institutions
- Jianghan University (CN)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2025-06-18
- DOI
- https://doi.org/10.3389/fnmol.2025.1596021
- Citations
- 1
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Jianghan University