Utilizing an Atomic Force Microscopy with Continuous Flow Injection Analysis using NAG-4(sources)x3 with Three Solar Cells (NAG-4SX3-3D) Analyzer for Studying the Surface Morphology of the Precipitate of the Cyproheptadine-HCl and Loratadine

The objective of this study is to describe surface morphology using Continuous Flow Injection Analysis CFIA, Atomic Force Microscopy AFM, and the homemade NAG-4(sources)x3 with three solar cell Analyzer NAG-4SX3-3D analyzer. Using a novel method for determining both drugs via reaction of both drugs, the study aims to determine the roughness parameters of (white precipitate of loratadine with sodium nitroprusside and yellow precipitate of cyproheptadine hydrochloride with 3,5-dinitro salicylic acid) for the AFM sample. The main advantage of the proposed technique is its ability to compute the amount of nanoparticles that can fill the empty surface area. Starting with the first ground, the monolayer calculates the free surface area and determines the concentration of the participating nanoparticles on the surface. A microfluidic flow system is thus proposed to produce nanoparticles on a continuous basis by means of a chemical reaction between precipitation reagents and medicinal active ingredients. The flow mechanism allows for the smooth and clog-free synthesis of the nanoparticles. Each and every chemical and physical flow injection conditions were examined and fixed. The average diameters of cyproheptadine hydrochloride for the surface area of a scanned section with dimensions of 20529961 nm2 and 1.6601 × 10-15 nmol/grain are 96.73 nm, Grain No. 547, surface area of a single granule 29380.015706 nm2, and number of layers 4; for loratadine, the average diameters are 88.87 nm, Grain No. 434, surface area of a single granule 24799.333466 nm2, and number of layers 1 for the scanned section whose dimensions are 10762910.72 nm2 and 1.3804 × 10-12 nmol/grain.