Uveal Melanoma and the Lynch Syndrome Tumor Spectrum
This prospective germline study on patients with UM provided evidence supporting the notion that MMR germline alterations are enriched among patients with UM and may contribute to oncogenesis of UM, and that UM may therefore be a rare tumor manifestation of Lynch syndrome.
Authors
- Livia Lumbroso‐Le Rouic (ORCID: https://orcid.org/0000-0003-2626-949X)
- Sophie Piperno‐Neumann (ORCID: https://orcid.org/0000-0001-9915-2810)
- Victor Renault (ORCID: https://orcid.org/0000-0001-8351-7168)
- Denis Malaise (ORCID: https://orcid.org/0000-0001-7454-819X)
- Nathalie Cassoux (ORCID: https://orcid.org/0000-0002-5535-9649)
- Fatoumata Simaga (ORCID: https://orcid.org/0009-0004-6277-7621)
- André Bortolini Silveira (ORCID: https://orcid.org/0000-0003-3375-1081)
- Kevin Merchadou
- Marc‐Henri Stern (ORCID: https://orcid.org/0000-0002-8100-2272)
- Chrystelle Colas (ORCID: https://orcid.org/0000-0001-9146-9346)
- Alexandre Matet (ORCID: https://orcid.org/0000-0002-9721-777X)
- Antoine De Pauw (ORCID: https://orcid.org/0000-0003-3898-073X)
- Alexandre Houy (ORCID: https://orcid.org/0000-0001-6267-2353)
- Manuel Rodrigues (ORCID: https://orcid.org/0000-0002-5443-0802)
- Julien Masliah‐Planchon (ORCID: https://orcid.org/0000-0002-5596-3926)
- Sophie El Zein (ORCID: https://orcid.org/0000-0001-6630-0020)
- Thibault Verrier (ORCID: https://orcid.org/0000-0002-5861-8423)
- Juliette Sauge (ORCID: https://orcid.org/0009-0009-5669-6186)
- Bruno Buecher (ORCID: https://orcid.org/0000-0003-0703-9082)
- Anne Vincent-Salomon
- Dominique Stoppa-Lyonnet
- Anaïs Le Ven (ORCID: https://orcid.org/0009-0007-9000-9349)
- Marie-Charlotte Villy
- Lisa Golmard
- Catherine Dubois d’Enghien
- Marion Gauthier‐Villars
- Marine Le Mentec
- Mathilde Warcoin
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Institut Curie (FR)
Publication Details
- Journal
- JAMA Ophthalmology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1001/jamaophthalmol.2025.1779
- Citations
- 2
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41