Psoriasis Risk in Patients With Atopic Dermatitis Treated With Dupilumab

The results of this cohort study suggest that patients with AD who were prescribed dupilumab exhibited a higher relative risk of developing psoriasis compared with those receiving other systemic agents. Given an estimated number needed to harm of 94, the absolute risk may have limited clinical relevance and should be weighed against dupilumab's established efficacy in treating AD.

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Publication Details

Journal
JAMA Dermatology
Published
2025-06-18
DOI
https://doi.org/10.1001/jamadermatol.2025.1578
Citations
17
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
34.08
Controls
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article

Psoriasis Risk in Patients With Atopic Dermatitis Treated With Dupilumab

Teng‐Li Lin, Yi‐Hsuan Fan, Yi–Ju Chen, Chao‐Kuei Juan et al.
17 citations
JAMA Dermatology
Dermatology and Skin Diseases
34.08
article

Psoriasis Risk in Patients With Atopic Dermatitis Treated With Dupilumab

Teng‐Li Lin, Yi‐Hsuan Fan, Yi–Ju Chen, Chao‐Kuei Juan, Chun-Ying Wu, Kuo-Sheng Fan
article en
17 citations

Abstract

The results of this cohort study suggest that patients with AD who were prescribed dupilumab exhibited a higher relative risk of developing psoriasis compared with those receiving other systemic agents. Given an estimated number needed to harm of 94, the absolute risk may have limited clinical relevance and should be weighed against dupilumab's established efficacy in treating AD.

JAMA DermatologyVol. 161(8)
National Yang Ming Chiao Tung University (TW), National Chung Hsing University (TW), China Medical University (TW), Taipei Veterans General Hospital (TW), Taichung Veterans General Hospital (TW), Chung Shan Medical University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 0%
Dermatology and Skin Diseases
34.08
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