Kidney transplant arteriopathy revisited

The frequent coincidence of transplant arteriopathy and indicators of antibody-mediated rejection suggests that this arterial remodelling could indeed be antibody-mediated rejection chronicity. The transplant community should re-examine transplant arteriopathy with an expanded definition including the previously ignored hypoelastotic lesion in order to re-confirm or reject with confidence transplant arteriopathy as Additional Diagnostic Parameter of Antibody-Mediated Rejection chronicity, and to learn about its prognostic and therapeutic implications.

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Publication Details

Journal
Journal of Nephrology
Published
2025-06-18
DOI
https://doi.org/10.1007/s40620-025-02308-3
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
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article

Kidney transplant arteriopathy revisited

Lutz T. Weber, Ulrike Bauernfeind, Georg Dieplinger, Tristan Cedric Wagner et al.
Journal of Nephrology
Renal Transplantation Outcomes and Treatments
article

Kidney transplant arteriopathy revisited

Lutz T. Weber, Ulrike Bauernfeind, Georg Dieplinger, Tristan Cedric Wagner, Ulrich Lang, Wolfgang Arns, Michael Nikolaus Thomas, Jan U. Becker, Dirk L. Stippel, Francesco Pesce, Katharina Wirths, Vanessa Ditt, Christine Kurschat, Hans Schlößer, Rabi Raj Datta, Michael A. Ströhlein
article en

Abstract

The frequent coincidence of transplant arteriopathy and indicators of antibody-mediated rejection suggests that this arterial remodelling could indeed be antibody-mediated rejection chronicity. The transplant community should re-examine transplant arteriopathy with an expanded definition including the previously ignored hypoelastotic lesion in order to re-confirm or reject with confidence transplant arteriopathy as Additional Diagnostic Parameter of Antibody-Mediated Rejection chronicity, and to learn about its prognostic and therapeutic implications.

Journal of NephrologyVol. 38(9)
University of Bonn (DE), Witten/Herdecke University (DE), University of Cologne (DE), Fatebenefratelli Hospital (IT), University Hospital Cologne (DE)
Good health and well-being
Openalex Percentile: Top 82%
Renal Transplantation Outcomes and Treatments
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Kidney transplant arteriopathy revisited — Lutz T. Weber, Ulrike Bauernfeind, et al. · Journal of Nephrology (2025) | TGRS Research Map | TGRS