Microsatellite instability as a possible diagnostic marker of the gastric mucosa dysplasia
Detection of microsatellite instability in gastric mucosa dysplasia indicates the likelihood of its occurrence at the early stages of the carcinogenesis cascade and makes it possible to use it to assess the risk of gastric cancer associated with microsatellite instability. The absence of instability in cases indefinite for dysplasia determines the possibility of its use for differential diagnosis of truly neoplastic and regenerative/reactive changes in the gastric mucosa.
Authors
- А. В. Кононов (ORCID: https://orcid.org/0000-0001-8607-7831)
- V. A. Rubtsov (ORCID: https://orcid.org/0000-0003-1834-3629)
- М. Н. Парыгина (ORCID: https://orcid.org/0000-0001-8006-3260)
- С. И. Мозговой (ORCID: https://orcid.org/0000-0001-7200-7082)
- A. G. Shimanskaya (ORCID: https://orcid.org/0000-0003-0949-8709)
- Е. Г. Поморгайло (ORCID: https://orcid.org/0000-0002-9857-1674)
- М. В. Маркелова (ORCID: https://orcid.org/0000-0002-5356-9669)
- E. Yu. Demidova
Institutions
- Omsk State Medical University (RU)
- Vector (United States) (US)
Publication Details
- Journal
- Russian Journal of Archive of Pathology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.17116/patol2025870315
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00