AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Our study demonstrates that AKR1C2 knockdown promotes ferroptosis and inhibits malignant biological behaviors in lung cancer cells.

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Publication Details

Journal
PLoS ONE
Published
2025-06-18
DOI
https://doi.org/10.1371/journal.pone.0325995
Citations
2
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
3.04
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article

AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Z. Liu, Yi Cui
2 citations
PLoS ONE
Ferroptosis and cancer prognosis
3.04
article

AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Z. Liu, Yi Cui
article en
2 citations

Abstract

Our study demonstrates that AKR1C2 knockdown promotes ferroptosis and inhibits malignant biological behaviors in lung cancer cells.

PLoS ONEVol. 20(6)
Guangzhou University of Chinese Medicine (CN), First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 9%
Ferroptosis and cancer prognosis
3.04
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AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells — Z. Liu, Yi Cui · PLoS ONE (2025) | TGRS Research Map | TGRS