Diethyl 2,2'-(1H-1,2,4-Triazole-3,5-diyl)diacetate: Synthesis Strategies, Chemical Behavior, Crystal Structure and Hirshfeld Surface Analysis
1,2,4-Triazolyl-3,5-diacetic acid ethyl ester was synthesized by condensation of hydrazine hydrate and N-acyl ethyl 3-ethoxy-3-iminopropanoate. Other methods for the synthesis are considered and their comparative analysis is carried out. The molecular structure of the title compound was established by X-ray analysis. Hirshfeld surface analysis was performed to investigate intermolecular interactions.
Authors
- Ilona V. Raspertova (ORCID: https://orcid.org/0000-0002-2382-063X)
- Rostyslav D. Lampeka (ORCID: https://orcid.org/0000-0001-8326-4535)
- Oleksandr V. Vashchenko (ORCID: https://orcid.org/0000-0002-5666-5592)
- Sergiu Shova
- Dmytro M. Khomenko (ORCID: https://orcid.org/0000-0001-7058-832X)
- Oleksandr S. Vynohradov
- V. V. Trachevskii
- R.A. Doroshchuk
Publication Details
- Published
- 2025-06-18
- DOI
- https://doi.org/10.23939/chcht19.02.221
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education and Science of Ukraine