Sodium-Glucose Cotransporter 2 Inhibitors Preceding ST-Segment Elevation Myocardial Infarction
SGLT2i appears to predominantly associate with up-regulation of heme-scavenging and nitric oxide, and plausibly through a related reduction in infarct size also associates with the observed related improvement in post infarction heart failure.
Authors
- George S. Katselis (ORCID: https://orcid.org/0000-0003-0869-7300)
- Paulos Chumala (ORCID: https://orcid.org/0000-0001-5026-4547)
- Jay Shavadia
- Rama Mangipudi
- Jacob A. Udell (ORCID: https://orcid.org/0000-0001-7402-9584)
- Haissam Haddad (ORCID: https://orcid.org/0000-0003-4821-3577)
- Megan Tomilin
Institutions
- University of Toronto (CA)
- Royal University Hospital (CA)
- University of Saskatchewan (CA)
- Canadian Rural Health Research Society (CA)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.jacadv.2025.101887
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Saskatchewan
- Royal University Hospital Foundation