Development and validation of a machine learning model to predict cognitive behavioral therapy outcome in obsessive-compulsive disorder using clinical and neuroimaging data
Machine learning models based on clinical data may thus hold promise in predicting remission after CBT for OCD, but the predictive power of multicenter rs-fMRI data is limited.
Authors
- Bjarne Hansen (ORCID: https://orcid.org/0000-0001-5659-1119)
- Sophia I. Thomopoulos (ORCID: https://orcid.org/0000-0002-0046-4070)
- Sara Bertolín (ORCID: https://orcid.org/0000-0003-1468-7862)
- Erika L. Nurmi (ORCID: https://orcid.org/0000-0003-4893-8957)
- Willem B. Bruin (ORCID: https://orcid.org/0000-0002-0672-8903)
- Eva Real (ORCID: https://orcid.org/0000-0003-4523-1649)
- Jamie D. Feusner (ORCID: https://orcid.org/0000-0002-0391-345X)
- John Piacentini (ORCID: https://orcid.org/0000-0003-4195-7194)
- Joyce Guo (ORCID: https://orcid.org/0000-0001-9388-6688)
- Anders Lillevik Thorsen (ORCID: https://orcid.org/0000-0003-2836-5223)
- Kristen Hagen (ORCID: https://orcid.org/0000-0002-4286-1277)
- Joseph O’Neill (ORCID: https://orcid.org/0000-0003-2216-3903)
- Odile A. van den Heuvel (ORCID: https://orcid.org/0000-0002-9804-7653)
- Dan Joseph Stein (ORCID: https://orcid.org/0000-0001-7218-7810)
- Guido van Wingen (ORCID: https://orcid.org/0000-0003-3076-5891)
- Ignacio Martínez‐Zalacaín (ORCID: https://orcid.org/0000-0002-4036-0284)
- José M. Menchón (ORCID: https://orcid.org/0000-0002-6231-6524)
- Laurens A. van de Mortel (ORCID: https://orcid.org/0000-0003-0567-340X)
- Cinto Segalàs (ORCID: https://orcid.org/0000-0002-0959-0356)
- Paul M. Thompson (ORCID: https://orcid.org/0000-0002-4720-8867)
- Pino Alonso (ORCID: https://orcid.org/0009-0000-1398-9821)
- Carles Soriano-Mas
Institutions
- South African Medical Research Council (ZA)
- University of Southern California (US)
- Netherlands Institute for Neuroscience (NL)
- Centre for Addiction and Mental Health (CA)
- California NanoSystems Institute (US)
- University of Cape Town (ZA)
- University of California, Los Angeles (US)
- Haukeland University Hospital (NO)
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Amsterdam Neuroscience (NL)
- University of California, Davis (US)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.jad.2025.119729
- Citations
- 2
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.61
Funders
- International OCD Foundation
- South African Medical Research Council
- Universitat de Barcelona
- Medical Research Council
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- Instituto de Salud Carlos III
- National Institute of Mental Health