Advancing beyond conventional vaccines: The potential of next-generation vaccines in combatting antibiotic-resistant bacteria
These bioinformatics approaches enable the identification of conserved antigenic targets across multiple strains of resistant bacteria. Multi-epitope vaccines, such as those based on recombinant proteins, DNA, or mRNA, offer the potential for broader protection and faster development timelines. Next-generation vaccines hold promise not only for enhancing immune responses but also for providing a safer and more scalable alternative to traditional vaccines against AMR.
Authors
- Damodharan Perumal
- Anandhakrishnan Rajaram Heamchandsaravanan (ORCID: https://orcid.org/0000-0003-3369-2587)
- Prabu Dhandapani (ORCID: https://orcid.org/0000-0003-2866-4338)
- Ragala Venkata Nandha
Institutions
- University of Madras (IN)
- Apollo Hospitals (IN)
Publication Details
- Journal
- Indian Journal of Medical Microbiology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.ijmmb.2025.100896
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00