Multidrug resistant Serratia fonticola: An emerging threat to human health and its implications

Serratia fonticola , a member of the Enterobacteriaceae family, a relatively uncommon human pathogen, is being increasingly recognised as a significant pathogen involved mainly in urinary tract infections (UTI). Despite its rarity, this microorganism has been linked to severe clinical manifestations, particularly in patients with underlying conditions or undergoing invasive procedures. There are increasing reports of multidrug resistance (MDR) among S. fonticola strains causing UTI, further complicating the treatment procedures. This review aims to highlight the evolution of MDR and its mechanisms in S. fonticola causing UTI in humans and their clinical implications. Furthermore, we are providing an update on infections caused by S. fonticola, including MDR strains, current strategies for the treatment, challenges, and future perspectives for effective prevention and control measures.

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Journal
The Microbe
Published
2025-06-18
DOI
https://doi.org/10.1016/j.microb.2025.100429
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
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article

Multidrug resistant Serratia fonticola: An emerging threat to human health and its implications

Shayan Ahmed, Qazi Mohd Rizwanul Haq, Syed A. A. Rizvi, M. W. Saif et al.
The Microbe
Antibiotic Resistance in Bacteria
article

Multidrug resistant Serratia fonticola: An emerging threat to human health and its implications

Shayan Ahmed, Qazi Mohd Rizwanul Haq, Syed A. A. Rizvi, M. W. Saif, Vikar Ahmed
article en

Abstract

Serratia fonticola , a member of the Enterobacteriaceae family, a relatively uncommon human pathogen, is being increasingly recognised as a significant pathogen involved mainly in urinary tract infections (UTI). Despite its rarity, this microorganism has been linked to severe clinical manifestations, particularly in patients with underlying conditions or undergoing invasive procedures. There are increasing reports of multidrug resistance (MDR) among S. fonticola strains causing UTI, further complicating the treatment procedures. This review aims to highlight the evolution of MDR and its mechanisms in S. fonticola causing UTI in humans and their clinical implications. Furthermore, we are providing an update on infections caused by S. fonticola, including MDR strains, current strategies for the treatment, challenges, and future perspectives for effective prevention and control measures.

The MicrobeVol. 8
Jamia Millia Islamia (IN)
Zero hunger
Openalex Percentile: Top 89%
Antibiotic Resistance in Bacteria
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Multidrug resistant Serratia fonticola: An emerging threat to human health and its implications — Shayan Ahmed, Qazi Mohd Rizwanul Haq, et al. · The Microbe (2025) | TGRS Research Map | TGRS