A semi-mechanistic pharmacokinetic/pharmacodynamic model for quantifying phage-antibiotic synergy against <i>Pseudomonas aeruginosa</i>
These promising findings support further <i>in</i> <i>vivo</i> validation and mechanistic studies to advance combination therapy for MDR pathogens. Our integrated approach paves way for clinical translation.
Authors
- Qixuan Hong
- Hak‐Kim Chan (ORCID: https://orcid.org/0000-0002-7054-3137)
- Yu-Wei Lin
- Sandra Morales (ORCID: https://orcid.org/0000-0001-7085-2864)
- Omar Assafiri (ORCID: https://orcid.org/0000-0002-7626-3099)
Institutions
- The University of Sydney (AU)
- Discovery Institute (US)
- Australian Regenerative Medicine Institute (AU)
- University of Malaya (MY)
- Link Consulting (PT)
- Monash University (AU)
Publication Details
- Journal
- Expert Opinion on Drug Delivery
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1080/17425247.2025.2520963
- Citations
- 2
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 3.43
Funders
- Australian Research Council