Electron donor–acceptor complex of aryl sulfonium salt enabling hydrogen/halogen atom transfer: C(sp<sup>3</sup>)–H alkylation of glycine derivatives and late-stage modification of peptides
Disclosed herein is the first example of visible-light-promoted C(sp<sup>3</sup>)-C(sp<sup>3</sup>) bond formation <i>via</i> a radical-radical coupling strategy, enabled by a sequential intermolecular charge transfer and atom transfer steps, for synthesizing unnatural amino acids and modifying peptides.
Authors
- Rupeng Qi
- Chenyang Zhang (ORCID: https://orcid.org/0000-0002-8351-7659)
- Mengran Wang
- Xiaobo Dang
- Zhaoqing Xu (ORCID: https://orcid.org/0000-0001-7663-6249)
- Qiao Chen (ORCID: https://orcid.org/0000-0001-5424-4818)
- Chao Wang (ORCID: https://orcid.org/0000-0001-9235-1243)
- Jinlong Shang
- Chun‐Lin Wang (ORCID: https://orcid.org/0000-0001-8120-8003)
- Xiao Song (ORCID: https://orcid.org/0009-0001-3675-1100)
Institutions
- Lanzhou University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03104d
- Citations
- 5
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 3.95