Impact of Low-Dose Ketamine Infusion on Intracranial Pressure and Hemodynamics in Septic Shock Patients
The present pilot study showed promising results of low-dose continuous ketamine infusion adjunctly on ICP and hemodynamics with a substantial reduction of sedatives and vasopressor dose. Further studies with large sample sizes and longer duration of administration and follow-up are needed to expand the current findings.
Authors
- Essamedin M. Negm (ORCID: https://orcid.org/0000-0003-3303-6870)
- Khaled Mohamed Altaher
- Ashraf Elsayed Ahmed
- Ahmed Morsy (ORCID: https://orcid.org/0000-0003-0937-9734)
- Ahmed Beniamen
- Hossam Tharwat Ali (ORCID: https://orcid.org/0000-0001-8077-5911)
- Hanaa A. Nofal (ORCID: https://orcid.org/0000-0002-5909-4238)
- Ahmed M. Gouda (ORCID: https://orcid.org/0000-0003-4527-8885)
- Marwan Elgohary
- Sherif Sharaf El Deen
- Ahmed Mosallem (ORCID: https://orcid.org/0000-0002-4363-800X)
- Tamer S. Elserafy
- Hani A. Albialy
Institutions
- South Valley University (EG)
- Zagazig University (EG)
Publication Details
- Journal
- Neurocritical Care
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1007/s12028-025-02302-4
- Citations
- 4
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Zagazig University
- South Valley University