Structured light imaging mesoscopy: detection of embedded morphological changes in superficial tissues
The findings establish the SLIM methodology as a means to detect morphological changes in an embedded subsurface tissue layer by leveraging inherent sensitivities of spatial frequency domain reflectance. This approach promises to enable simplified clinical tracking of subsurface microstructural alterations without the explicit need to consider an inverse problem approach.
Authors
- Mahsa Parsanasab
- Kavon Karrobi (ORCID: https://orcid.org/0000-0001-7034-6937)
- Darren Roblyer (ORCID: https://orcid.org/0000-0002-5301-4364)
- Vasan Venugopalan (ORCID: https://orcid.org/0000-0003-4781-1049)
- Aarohi M. Mehendale (ORCID: https://orcid.org/0000-0002-4737-0178)
Institutions
- Boston University (US)
- University of California, Irvine (US)
- Beckman Laser Institute and Medical Clinic (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1117/1.jbo.30.6.065001
- Citations
- 1
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Boston University
- National Scleroderma Foundation