Antidiabetic sitagliptin influences tissue regeneration by affecting progenitor cells
Sitagliptin treatment may have positive effects on ulcer healing in diabetics. However, the possible changes produced in serum composition may negatively affect bone formation. Therefore, sitagliptin may affect regenerative capacity and induce different responses in progenitor cells, depending on their niche.
Authors
- María Ángeles Gálvez-Moreno
- Aura D. Herrera‐Martínez (ORCID: https://orcid.org/0000-0003-1437-9878)
- Paloma Moreno-Moreno (ORCID: https://orcid.org/0000-0002-7297-9399)
- José Manuel Quesada‐Gómez (ORCID: https://orcid.org/0000-0003-0990-5650)
- Antonio Casado‐Díaz (ORCID: https://orcid.org/0000-0002-8520-8278)
- Marta Camacho-Cardeñosa (ORCID: https://orcid.org/0000-0002-0921-2670)
- Victoria Pulido-Escribano (ORCID: https://orcid.org/0000-0002-1107-1547)
- Bárbara Torrecillas-Baena (ORCID: https://orcid.org/0000-0001-6934-3958)
- Gabriel Dorado
Institutions
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Hospital Universitario Reina Sofía (ES)
- Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.biopha.2025.118279
- Citations
- 1
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable
- European Commission
- Ministerio de Ciencia e Innovación
- Instituto de Salud Carlos III
- Center for International Business Education and Research, University of Illinois at Urbana-Champaign