Treatment and outcomes of local re-recurrence in rectal cancer: a multicentre observational cohort
The median OS in 277 LrRRC patients was 23 months. Aggressive treatment in selected patients resulted in a median OS of 35 months. Furthermore, locoregional control was achieved for 11 months in patients undergoing surgery. These findings underscore the need for meticulous patient selection and tailored treatment strategies to improve survival while minimising unnecessary morbidity.
Authors
- Cornelis Verhoef (ORCID: https://orcid.org/0000-0001-9980-8613)
- Heike Peulen (ORCID: https://orcid.org/0000-0003-3752-8274)
- Jacobus W. A. Burger (ORCID: https://orcid.org/0000-0003-1988-0186)
- Geert-Jan Creemers (ORCID: https://orcid.org/0000-0002-9358-1996)
- Paul Harmsen
- Stefi Nordkamp (ORCID: https://orcid.org/0000-0002-9738-8691)
- Stijn H. J. Ketelaers (ORCID: https://orcid.org/0000-0002-0756-5894)
- F Piqeur
- Jip L. Tolenaar
- Grard A. P. Nieuwenhuijzen (ORCID: https://orcid.org/0000-0002-5837-5513)
- Johanne G. Bloemen
- An-Sofie Verrijssen (ORCID: https://orcid.org/0000-0002-5193-2831)
- H.M.W. Verheul
- Joost Nederend (ORCID: https://orcid.org/0000-0002-9905-5866)
- Joost Rothbarth
- Irene E.G. van Hellemond (ORCID: https://orcid.org/0009-0005-9513-7126)
- H.J.T. Rutten (ORCID: https://orcid.org/0000-0003-2532-950X)
- David M Mens (ORCID: https://orcid.org/0009-0000-2247-5048)
- Davy M J Creemers (ORCID: https://orcid.org/0009-0005-8444-3865)
- Evi Banken (ORCID: https://orcid.org/0009-0002-6684-0101)
- R R J Coebergh-van den Braak
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Maastricht University (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1016/j.ejso.2025.110261
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00