Glofitamab Combined With Pola-R-CHP or R-CHOP as First Therapy in Younger Patients With High-Risk Large B-Cell Lymphoma: Results From the COALITION Study

The combination of glofitamab with R-CHOP or Pola-R-CHP is deliverable and results in high rates of durable response in this population of younger patients with high-burden, HR LBCL, supporting its ongoing exploration as a 1L treatment.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2025-06-18
DOI
https://doi.org/10.1200/jco-25-00481
Citations
5
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
7.36
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article

Glofitamab Combined With Pola-R-CHP or R-CHOP as First Therapy in Younger Patients With High-Risk Large B-Cell Lymphoma: Results From the COALITION Study

Emma Verner, Thiago M. Steiner, Javad Saghebi, Adrian Minson et al.
5 citations
Journal of Clinical Oncology
Lymphoma Diagnosis and Treatment
7.36
article

Glofitamab Combined With Pola-R-CHP or R-CHOP as First Therapy in Younger Patients With High-Risk Large B-Cell Lymphoma: Results From the COALITION Study

Emma Verner, Thiago M. Steiner, Javad Saghebi, Adrian Minson, Molly Robertson, Sumita Ratnasingam, Wojciech Janowski, Fiona Swain, Mark P. Hertzberg, Paul J. Neeson, Rory Bennett, Jason M. Butler, Sean Harrop, Piers A. Blombery, Costas K. Yannakou, Chan Yoon Cheah, Matthew Ku, Nada Hamad, John Francis Seymour, Sally M. Hunter, Lei Shong Lau, Jing Xie, Michael John Dickinson, Kirsten Herbert, Shu Min Wong, Pratyush Giri
article en
5 citations

Abstract

The combination of glofitamab with R-CHOP or Pola-R-CHP is deliverable and results in high rates of durable response in this population of younger patients with high-burden, HR LBCL, supporting its ongoing exploration as a 1L treatment.

Journal of Clinical OncologyVol. 43(23)
Royal Adelaide Hospital (AU), The Royal Melbourne Hospital (AU), The University of Queensland (AU), The University of Melbourne (AU), Royal Brisbane and Women's Hospital (AU), Geelong Hospital (AU), Epworth Hospital (AU), Concord Repatriation General Hospital (AU), Peter MacCallum Cancer Centre (AU), Princess Alexandra Hospital (AU), The Alfred Hospital (AU), Sir Charles Gairdner Hospital (AU), St Vincent's Hospital Melbourne (AU), St Vincent's Hospital Sydney (AU), Cabrini Hospital (AU), Prince of Wales Hospital (AU), Calvary Mater Newcastle Hospital (AU)
Openalex Percentile: Top 3%
Lymphoma Diagnosis and Treatment
7.36
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